Tri-Mix simply means that there are three medications combined in one solution.

TRIMIX is insurance in a syringe.

Build confidence, stretch the tissues, perform well, and experience intense pleasure when using Tri-Mix, also known as Intra-cavernosal injection (ICI), as an erection rescue for many men.  ICI is a painless injection of a medication containing vasodilators into the shaft of the penis to cause an erection. Most men will use Tri-Mix with great success.

There is important information you need to know about this class of medication so that you can use it effectively and safely. There are real dangers if you are not prescribed the correct dose or if you inject the medication improperly or too frequently. 

The three medications in Tri-Mix are Papaverine, Phentolamine and Prostaglandin E1.

The Doctors Studio Team spends time properly fitting you to the correct medication dose while teaching you excellent injection techniques so that the complications and risks of Tri-Mix are minimized. We provide you with an auto-injector device that makes injecting painless and mistake-proof. Good technique and careful attention to detail allow the use of these medications for years as the sole treatment of choice or as insurance in cases when sexual anxiety could be a problem. They can be used temporarily in conjunction with regenerative treatments such as P-Shot ( and Shock Wave Therapy (

A Penile Duplex Doppler Ultrasound ( is done to evaluate the blood flow into your penis and the presence or absence of venous leakage. The information from the doppler ultrasound is used to “fit” you with the correct dose and combination of medications.  

The strength of these medications can be customized to the patient’s needs.  There is no real “STANDARD DOSE”. 

ICI Medications (penis injections) are customized for men of all ages with unique combinations and strengths for your specific erection and sexual problems.

Here are the common combinations:

  • Alprostadil (Prostaglandin E-1): For men with mild to moderate ED but can cause discomfort in some men
  • BI-MIX:  Papaverine and Phentolamine: For men who cannot tolerate Prostaglandin E-1
  • TRI-MIX:  Papaverine, Phentolamine and PGE-1: Most common combination
  • QUAD-MIX:  Papaverine, Phentolamine, PGE-1 and Atropine: For more severe ED

How can I start treatment?

  • Get fit with the correct, effective medication dose
  • You receive proper education about administering medication and what to do if a complication does arise
  • You are provided medication to take home to administer when desired.

ICI is often used for men who do not respond to oral medications such as Cialis, Viagra, and Levitra. It can be used in men who have side effects with the oral medications and also for those who prefer the control and predictability Tri-Mix or other custom ICI medications provide. 

The use of ICI in men with PE is a game changer!

Men who have premature ejaculation (PE) can have great success with the Tri-Mix (ICI) because the dose can be selected so that they can continue having a rigid erection even after ejaculation. This allows them to continue the sexual act for a longer period than would have been possible without the medication. They can therefore pleasure their partner and they may eventually become desensitized to the point of having more control over ejaculation. 

TRIMIX and Customized ICI Medication BENEFITS:

  • Reliable and predictable erections
  • Staying power after ejaculation
  • More rigid erections
  • Better sensitivity and more intense orgasm

Don’t Know Where to Start?

The Studio Team is here to serve you.